Blood glucose Monitoring of blood glucose is important in diabetics, in particular in the presence of hypokalaemia. Uric acid Tendency to gout attacks may be increased in hyperuricaemic patients. In the elderly, this plasma creatinine must be adjusted in relation to age, weight and gender. Hypovolaemia, secondary to the loss of water and sodium induced by the diuretic at the start of treatment causes a reduction in glomerular filtration.
This may lead to an increase in blood urea and plasma creatinine. This transitory functional renal insufficiency is of no consequence in individuals with normal renal function but may worsen pre-existing renal insufficiency. Athletes The attention of athletes is drawn to the fact that this medicinal product contains a drug substance, which may give a positive reaction in doping tests. However, if the use of diuretics is necessary, careful monitoring of plasma lithium and dose adjustment are required.
Combinations requiring precautions for use Torsades de pointes-inducing drugs - class Ia antiarrhythmics quinidine, hydroquinidine, disopyramide , - class III antiarrhythmics amiodarone, sotalol, dofetilide, ibutilide , - some antipsychotics: Increased risk of ventricular arrhythmias, particularly torsades de pointes hypokalaemia is a risk factor.
Monitor for hypokalaemia and correct, if required, before introducing this combination. Clinical, plasma electrolytes and ECG monitoring. Use substances which do not have the disadvantage of causing torsades de pointes in the presence of hypokalaemia. Risk of acute renal failure in dehydrated patients decreased glomerular filtration. Hydrate the patient; monitor renal function at the start of treatment. In hypertension, when prior diuretic treatment may have caused sodium depletion, it is necessary: In congestive heart failure, start with a very low dose of ACE inhibitor, possibly after a reduction in the dose of the concomitant hypokalaemic diuretic.
In all cases, monitor renal function plasma creatinine during the first weeks of treatment with an ACE inhibitor. Other compounds causing hypokalaemia: Monitoring of plasma potassium and correction if required. Hypokalemia can sensitize or exaggerate the response of the heart to the toxic effects of digitalis, such as increased ventricular irritability. Dilutional hyponatremia may occur in edematous patients; the appropriate treatment is restriction of water rather than administration of salt, except in rare instances when the hyponatremia is life threatening.
However, in actual salt depletion, appropriate replacement is the treatment of choice. Any chloride deficit that may occur during treatment is generally mild and usually does not require specific treatment except in extraordinary circumstances as in liver or renal disease. Thiazide-like diuretics have been shown to increase the urinary excretion of magnesium; this may result in hypomagnesemia. Hyperuricemia and Gout Serum concentrations of uric acid increased by an average of 0.
Serum concentrations of uric acid should, therefore, be monitored periodically during treatment. Renal Impairment Indapamide, like the thiazides, should be used with caution in patients with severe renal disease, as reduced plasma volume may exacerbate or precipitate azotemia. If progressive renal impairment is observed in a patient receiving Indapamide, withholding or discontinuing diuretic therapy should be considered. Renal function tests should be performed periodically during treatment with Indapamide.
Impaired Hepatic Function Indapamide, like the thiazides, should be used with caution in patients with impaired hepatic function or progressive liver disease, since minor alterations of fluid and electrolyte balance may precipitate hepatic coma. Glucose Tolerance Latent diabetes may become manifest and insulin requirements in diabetic patients may be altered during thiazide administration. A mean increase in glucose of 6. Serum concentrations of glucose should be monitored routinely during treatment with Indapamide.
Calcium Excretion Calcium excretion is decreased by diuretics pharmacologically related to Indapamide. After 6 to 8 weeks of Indapamide 1. Remember that your doctor has prescribed Natrilix Indapamide 2. Many people using Natrilix Indapamide 2. Tell your doctor right away if you have any symptoms of dehydration or mineral loss, including: Tell your doctor right away if you have any serious side effects, including: A very serious allergic reaction to Natrilix Indapamide 2.
However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at Click here to view a more detailed list of Natrilix side effects. If you miss a dose of Natrilix Indapamide 2. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Pregnancy and breast-feeding Indapamide is not recommended during pregnancy. Talk to your doctor before taking this medicine if you are pregnant, might become pregnant, or think you may be pregnant.
Do not use this medicine if you are breast-feeding or planning to breast-feed. If you have been told by your doctor that you cannot digest or tolerate some sugars, talk to your doctor before taking this medicine. You should check with your doctor or pharmacist if you are not sure.
Taking this medicine Keep taking this medicine until your doctor tells you to stop. It may take several months before this medicine shows its full effect. Tablets can be taken with or without food Swallow the tablets whole with a drink of water Adults and Elderly The usual dose is one tablet, once a day, taken in the morning If you take more indapamide than you should If you take more tablets than you should, tell your doctor or go to your nearest hospital casualty department immediately.
Take the carton and any indapamide tablets left with you so that the doctors know what you have taken. Taking too much indapamide may make you feel or be sick nausea or vomiting , cause low blood pressure, cramps, dizziness, drowsiness, confusion and changes in the amount of urine produced by the kidneys due to severe dehydration.
If you forget to take indapamide Do not take a double dose to make up for a forgotten tablet. Miss it out and take the next dose at the usual time. If you stop taking indapamide Keep taking indapamide until your doctor tells you to stop taking it.
Treatment for high blood pressure is usually life-long. If you have any further questions on the use of this medicine, ask your doctor or pharmacist. Stop taking indapamide and see your doctor immediately or go to a hospital straight away if you experience any of the following side effects: Angioedema is characterised by swelling of the skin around the eyes, lips, tongue, hands or feet. It may cause swelling of the throat, tongue or airways resulting in shortness of breath or difficulty in swallowing.
If this occurs, contact your doctor immediately; severe skins reactions including intense skin rash, reddening of the skin over your whole body, severe itching, blistering, peeling and swelling of the skin, inflammation of mucous membranes, flu-like symptoms and fever Stevens-Johnson Syndrome or other allergic reactions; you get an irregular heartbeat Torsade de pointes , which could be life-threatening; severe stomach pain which may reach through to your back.
This could be a sign of pancreatitis; abnormal liver function with symptoms such as tiredness, loss of appetite, feeling or being sick, swollen extremities, yellow skin ; in cases of liver failure, there is a possibility of getting hepatic encephalopathy liver problems which affect the brain and central nervous system. Tell your doctor as soon as possible if you have any of the following side-effects:
If you forget to take indapamide Do not take a double dose to make up for a forgotten tablet. 5mg is hypervolemia during normal pregnancy which is not harmful to either the fetus or the mother in the absence of cardiovascular diseaseindapamide 2 5mg, but which is associated with edema, including generalized edema in the majority of pregnant women. You get increased thirst, hunger and weight loss. Indapamide had an antihypertensive effect in patients with varying degrees of renal impairment, although in general, diuretic effects declined as renal function decreased. High blood pressure hypertension. If you notice other effects not listed above, contact your doctor or pharmacist, indapamide 2 5mg. Cases of photosensitivity reactions change in skin appearance after exposure indapamide the sun or artificial UVA have also been reported. Hypokalaemia, as well as bradycardia, is then a predisposing factor to the onset of severe arrhythmias, in particular, potentially fatal torsades de pointes. Calcium salts Risk of hypercalcaemia resulting from decreased urinary elimination of calcium. Indapamide your doctor for medical advice about side effects. Detection of hypokalaemia requires its correction. Angioedema is characterised 5mg swelling of the skin around the eyes, lips, tongue, indapamide 2 5mg, hands or feet. It may harm them, even if their symptoms are the same as yours. If photosensitivity reaction occurs during treatment, it is recommended to stop the treatment. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Interference with adequate oral intake of electrolytes will also contribute to hypokalemia. If this edema produces discomfort, increased recumbency will often provide relief.
The indapamide changes in your blood test results may occur: Dizziness or headache may occur. The risk of hypokalemia secondary to diuresis and natriuresis is increased when larger doses are used, when the diuresis is brisk, when severe cirrhosis is present, and during concomitant use of corticosteroids or ACTH. Keep taking 5mg Indapamide 2. Other compounds causing hypokalaemia: Imipramine-like antidepressants, neuroleptics Antihypertensive effect and increased risk of orthostatic hypotension increased additive effect. Monitoring of plasma potassium and ECG indapamide, if necessary, adjust the treatment. You may also have a high temperature, sore throat, headache or diarrhoea You get more infections than usual or bruise more easily. It is a white to yellow-white crystalline tetragonal powder, indapamide 2 5mg. If a single daily tablet of indapamide does not 5mg a sufficient reduction in blood pressure, another antihypertensive agent may be added; those which have been used in combination with indapamide include beta-blockers, ACE inhibitors, methyldopa, clonidine and other adrenergic blocking agents. Tell your doctor right away if you have any symptoms of dehydration or mineral loss, including: You should not take indapamide with lithium due to the risk of increased levels of lithium in the blood medicines for heart rhythm problems such as quinidine, hydroquinidine, indapamide 2 5mg, disopyramide, amiodarone, sotalol, ibutilide, dofetilide or digitalis bepridil used indapamide treat angina pectoris, a condition causing chest pain stimulant laxatives medicines used to treat 5mg disorders such as depression, indapamide or schizophrenia for example tricyclic antidepressants, antipsychotic drugs, neuroleptics sparfloxacin, indapamide 2 5mg, moxifloxacin, erythromycin by injection antibiotics used to treat infections vincamine by injection used to treat symptomatic cognitive disorders in elderly including memory loss pentamidine used to treat certain types of pneumonia halofantrine antiparasitic drug used to treat certain types of malaria mizolastine used to treat allergic reactions, such as hay fever non-steroidal anti-inflammatory drugs for cialis 5mg cheapest relief verapamil 180mg er. This medicine has been prescribed for you only. Pharmaceutical form Round, indapamide 2 5mg, white, film-coated tablet with S6 stamped on one side 4, indapamide 2 5mg. It 5mg take up to several weeks before you get the full benefit of Natrilix Indapamide 5mg.
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